Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 13/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324623 | 0.81 | TSHR (0.49) | PTGS1PTGS2ALDH1A1ERBB2MAPK1 | |
| SCHEMBL6332471 | 0.81 | ALDH1A1 (0.57) | PTGS1PTGS2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9137301 | 0.78 | TSHR (0.56) | ALDH1A1MAPK1HSD17B10TSHRTP53 | |
| SCHEMBL9339338 | 0.75 | PTGS1 (0.58) | PTGS1PTGS2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9853804 | 0.75 | PTGS1 (0.62) | PTGS1PTGS2ALDH1A1MAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9853805 | 0.74 | PTGS1 (0.60) | PTGS1PTGS2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL11543748 | 0.73 | PTGS1 (0.51) | PTGS1PTGS2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4372207 | 0.72 | PTGS1 (1.00) | PTGS1PTGS2 | |
| SCHEMBL31061517 | 0.72 | PTGS1 (0.76) | PTGS1PTGS2 | |
| SCHEMBL23319507 | 0.72 | ALDH1A1 (0.54) | PTGS1PTGS2ALDH1A1HSD17B10KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |