SCHEMBL1154518

SCHEMBL1154518

C=CCC1C(=O)NC(=O)C1CC=C

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
PRSS1 P07477 2/20 0.37
CTRC Q99895 2/20 0.37
F2 P00734 1/20 0.37
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559041 0.71 ALDH1A1 (0.37) ALDH1A1PRSS1CTRCF2
SCHEMBL472480 0.70 ALDH1A1 (0.72) ALDH1A1GAAHPGDMAPK1MAPT
SCHEMBL28820651 0.69 ALDH1A1 (0.38) ALDH1A1PRSS1CTRCF2
SCHEMBL5329424 0.69 ALDH1A1 (1.00) ALDH1A1GAAHPGDMAPK1MAPT
SCHEMBL17294189 0.69 ALDH1A1 (0.69) ALDH1A1GAAHPGDMAPK1MAPT
SCHEMBL15672438 0.68 PRSS1 (0.46) ALDH1A1PRSS1CTRCF2
SCHEMBL1483113 0.68 ALDH1A1 (0.52) ALDH1A1GAAHPGDMAPK1MAPT
SCHEMBL8252001 0.68 IDUA (0.41) ALDH1A1PRSS1CTRCF2
SCHEMBL2143425 0.67 ALDH1A1 (0.50) ALDH1A1GAAHPGDMAPK1MAPT
SCHEMBL10489775 0.66 TSHR (0.52) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305759-B1 NONPOLAR LIQUID AND SOLID PHASE CHANGE INK COMPOSITIONS COMPRISING NANOSIZED PARTTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORP (US) 2017-09-06 EP disclosed
US-8461351-B2 Sterically bulky stabilizers XEROX CORPORATION (US) 2013-06-11 US disclosed
US-8455654-B2 Nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2013-06-04 US disclosed
US-8426636-B2 Sterically bulky stabilizers XEROX CORPORATION (US) 2013-04-23 US disclosed
US-20110277668-A1 STERICALLY BULKY STABILIZERS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-11-17 US disclosed
US-20110271874-A1 Nanosized Particles of Benzimidazolone Pigments NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-11-10 US disclosed
US-8025723-B2 Nonpolar liquid and solid phase change ink compositions comprising nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2011-09-27 US disclosed
US-8012254-B2 Nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2011-09-06 US disclosed
US-7985290-B2 Nonpolar liquid and solid phase change ink compositions comprising nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2011-07-26 US disclosed
US-7938903-B2 Nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2011-05-10 US disclosed
US-20100300326-A1 NONPOLAR LIQUID AND SOLID PHASE CHANGE INK COMPOSITIONS COMPRISING NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-12-02 US disclosed
US-20100251928-A1 NONPOLAR LIQUID AND SOLID PHASE CHANGE INK COMPOSITIONS COMPRISING NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-10-07 US disclosed
EP-2196504-A2 Method of making nanoscale particles of AZO pigments in a microreactor or micromixer Xerox Corporation (US) 2010-06-16 EP disclosed
US-20100104963-A1 NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-04-29 US disclosed
US-20100037955-A1 NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-02-18 US disclosed
US-20100035172-A1 NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-02-11 US disclosed
US-20100004360-A1 METHODS OF MAKING NANOSIZED PARTICLES OF BENZIMIDAZOLONE PIGMENTS XEROX CORPORATION (US) 2010-01-07 US disclosed
EP-2110412-A2 Nanosized particles of benzimidazolone pigments Xerox Corporation (US) 2009-10-21 EP disclosed
US-7563318-B1 Method of making nanoscale particles of AZO pigments in a microreactor or micromixer XEROX CORPORATION (US) 2009-07-21 US disclosed
US-7503973-B1 Nanosized particles of benzimidazolone pigments XEROX CORPORATION (US) 2009-03-17 US disclosed