Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172646 | 0.82 | PSIP1 (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL19776259 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAHPGDCA2 | |
| SCHEMBL14018774 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GAASMN1; SMN2LMNAHPGD | |
| SCHEMBL28486120 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2LMNAHTT | |
| SCHEMBL11570200 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAHTTCA2 | |
| SCHEMBL27491708 | 0.80 | GBA1 (0.46) | ALDH1A1GAASMN1; SMN2HPGDCA2 | |
| SCHEMBL769089 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2LMNAHPGD | |
| SCHEMBL13956708 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GAASMN1; SMN2LMNAHPGD | |
| SCHEMBL29134162 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTCA2 | |
| SCHEMBL29278756 | 0.79 | GAA (0.52) | ALDH1A1GAASMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147870-A | REACTION OF ACYLAZIRIDINE WITH MONOSULFONYL DERIVATIVE OF PIPERAZINE | LABORATORIOS LIADE, S.A. (ES) | 1979-04-03 | — | — | US | disclosed |