Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674103 | 0.92 | CA12 (0.59) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL5929599 | 0.85 | IGF1R (0.45) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL11545447 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL27940729 | 0.81 | KMT2A (0.47) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL14018774 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL11570200 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CA12CA9CA2CYP3A4 | |
| SCHEMBL10985034 | 0.78 | KEAP1 (0.53) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL13956708 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL769089 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CA12CA9CA1CA2 | |
| SCHEMBL27491708 | 0.77 | GBA1 (0.46) | ALDH1A1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997425-B | Method for preparing high-content fosfomycin trometamol | 湖南华纳大药厂手性药物有限公司 | 2020-11-13 | — | — | CN | disclosed |