Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 8/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1382900 | 0.86 | MEN1 (0.43) | MEN1KMT2ALMNACASP3SENP8 | |
| SCHEMBL10946051 | 0.85 | MEN1 (0.43) | MEN1KMT2ALMNACASP3SENP8 | |
| SCHEMBL13811021 | 0.85 | MEN1 (0.43) | MEN1KMT2ALMNACASP3SENP8 | |
| SCHEMBL9723244 | 0.85 | MAPT (0.45) | MEN1KMT2ALMNACASP3SENP8 | |
| SCHEMBL29210204 | 0.85 | MEN1 (0.48) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11072798 | 0.82 | MAOA (0.53) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL11065509 | 0.80 | MAOA (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10943626 | 0.78 | LMNA (0.39) | MEN1KMT2ALMNACASP3SENP8 | |
| SCHEMBL10949964 | 0.78 | SMN1; SMN2 (0.39) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL10942288 | 0.78 | SMN1; SMN2 (0.39) | MEN1KMT2ALMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |