Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545784 | 0.77 | CTSB (0.57) | CTSBNOX4KDM4EALDH1A1LMNA | |
| SCHEMBL11545045 | 0.75 | CTSB (0.57) | CTSBNOX4KDM4EALDH1A1LMNA | |
| SCHEMBL25197942 | 0.73 | CTSB (0.51) | CTSBNOX4PITRM1HIF1AKDM4E | |
| SCHEMBL25416781 | 0.70 | CTSB (0.71) | CTSBNOX4HIF1AKDM4EMAPT | |
| SCHEMBL25188234 | 0.69 | CTSB (0.61) | CTSBNOX4PITRM1HIF1AKDM4E | |
| SCHEMBL25193605 | 0.69 | CTSB (0.61) | CTSBNOX4PITRM1HIF1AKDM4E | |
| SCHEMBL25191957 | 0.69 | CTSB (0.61) | CTSBNOX4PITRM1HIF1AKDM4E | |
| SCHEMBL13690792 | 0.68 | CTSB (0.51) | CTSBNOX4PITRM1HIF1AKDM4E | |
| SCHEMBL4231830 | 0.66 | ALDH1A1 (0.58) | CTSBNOX4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25195450 | 0.65 | CTSB (0.60) | CTSBNOX4PITRM1HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163852-A | Process for the preparation of tetrahydro-thieno[3,2-c]- and [2,3-c]pyridine derivatives | PARCOR (FR) | 1979-08-07 | — | — | US | disclosed |