Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545045 | 0.91 | CTSB (0.57) | CTSBALDH1A1LMNACYP2C19USP2 | |
| SCHEMBL10620313 | 0.81 | KDM4E (0.55) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| SCHEMBL11542759 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| SCHEMBL11548136 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| SCHEMBL25416781 | 0.78 | CTSB (0.71) | CTSBALDH1A1LMNAUSP2SMN1; SMN2 | |
| SCHEMBL11548022 | 0.78 | ALDH1A1 (0.72) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| SCHEMBL11545586 | 0.77 | CTSB (0.46) | CTSBALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL11542152 | 0.77 | CYP2C19 (0.54) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| SCHEMBL10625293 | 0.76 | ALDH1A1 (0.63) | ALDH1A1LMNACYP2C19USP2ABCB11 | |
| Hydrochloric Acid SCHEMBL11705496 | 0.75 | KDM4E (0.64) | ALDH1A1LMNACYP2C19USP2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163852-A | Process for the preparation of tetrahydro-thieno[3,2-c]- and [2,3-c]pyridine derivatives | PARCOR (FR) | 1979-08-07 | — | — | US | disclosed |