Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544482 | 0.80 | MEN1 (0.45) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL18203120 | 0.79 | KDM4E (0.36) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11547901 | 0.73 | EDNRA (0.43) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL8117184 | 0.71 | CYP1A2 (0.50) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11547366 | 0.71 | CYP1A2 (0.45) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11545777 | 0.69 | MAPT (0.37) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11549835 | 0.67 | S100A4 (0.54) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11545827 | 0.67 | CYP1A2 (0.45) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL14665269 | 0.67 | MAPT (0.45) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL11642874 | 0.66 | TOP1 (0.40) | MAPTLMNACYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151182-A | CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) | 1979-04-24 | — | — | US | disclosed |