Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117184 | 0.82 | CYP1A2 (0.50) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL27855142 | 0.81 | AR (0.42) | CYP1A2MAPK1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL15251855 | 0.80 | CYP19A1 (0.43) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL6203908 | 0.78 | SMN1; SMN2 (0.42) | CYP1A2MAPK1LMNATP53ALDH1A1 | |
| SCHEMBL11547366 | 0.77 | CYP1A2 (0.45) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL11549835 | 0.77 | S100A4 (0.54) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL11012570 | 0.76 | LMNA (0.48) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL27297541 | 0.74 | EDNRA (0.52) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL15449470 | 0.74 | MEN1 (0.46) | CYP1A2MAPK1LMNATP53CYP3A4 | |
| SCHEMBL29475772 | 0.73 | CYP2D6 (0.51) | CYP1A2MAPK1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482236-A | Indanone derivatives and pharmaceutical compositions containing the same | KOREA RES INST CHEM TECH | 2012-05-30 | — | — | CN | disclosed |
| US-4151182-A | CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) | 1979-04-24 | — | — | US | disclosed |