Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546784 | 0.90 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL9346820 | 0.89 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL11548779 | 0.89 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL23110719 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL11027291 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL20030505 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP3A4MAPK1MAPTLMNA | |
| SCHEMBL5642200 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL2373598 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRMAPK1MAPT | |
| SCHEMBL5732683 | 0.81 | PIN1 (0.49) | ALDH1A1CYP3A4MAPTVCAM1PIN1 | |
| SCHEMBL11548343 | 0.79 | TDP1 (0.49) | ALDH1A1CYP3A4MAPK1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |