Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741522 | 0.90 | NR4A2 (0.61) | NR4A2NR4A1NR4A3KMT2ANPC1 | |
| SCHEMBL11546333 | 0.85 | CYP1A2 (0.65) | NR4A2MRGPRX4CYP1A2KMT2AMEN1 | |
| SCHEMBL11545229 | 0.85 | NR4A2 (0.56) | NR4A2MRGPRX4NR4A1NR4A3KMT2A | |
| SCHEMBL11544924 | 0.85 | NR4A2 (0.56) | NR4A2MRGPRX4NR4A1NR4A3KMT2A | |
| SCHEMBL11549132 | 0.83 | NR4A2 (0.67) | NR4A2NR4A1NR4A3KMT2AMEN1 | |
| SCHEMBL11549983 | 0.82 | PPARA (0.61) | MRGPRX4KMT2AMEN1TAAR1NPC1 | |
| SCHEMBL7389290 | 0.82 | PRSS1 (0.56) | CYP1A2 | |
| SCHEMBL6938286 | 0.82 | CYP1A2 (0.63) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8417231 | 0.81 | KMT2A (0.63) | NR4A2NR4A1NR4A3KMT2APLA2G4B | |
| Benzoic Acid SCHEMBL28105551 | 0.80 | KMT2A (0.54) | NR4A2MRGPRX4CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073935-A | Substituted propanol-(2)-derivatives and their nicotinic acid esters, and process for their preparation, and the use thereof as hypolipemic drugs | KLINGE PHARMA GMBH & CO. (DT) | 1978-02-14 | — | — | US | claimed |
| US-4144351-A | ANTICHOLESTEROL | KLINGE PHARMA GMBH & CO. (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4109013-A | SUBSTITUTED PROPANOL-(2) DERIVATIVES OF HYDROXAMIC ACIDS AND THE USE THEREOF AS HYPOLIPEMIC DRUGS | KLINGE PHARMA GMBH & CO. (DE) | 1978-08-22 | — | — | US | disclosed |
| US-4073935-A | Substituted propanol-(2)-derivatives and their nicotinic acid esters, and process for their preparation, and the use thereof as hypolipemic drugs | KLINGE PHARMA GMBH & CO. (DT) | 1978-02-14 | — | — | US | disclosed |