Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545678 | 0.96 | NAAA (0.55) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19149703 | 0.89 | MMP2 (0.52) | HDAC3NPC1RAB9AFOLH1 | |
| SCHEMBL11544593 | 0.88 | FOLH1 (0.60) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10801036 | 0.88 | FOLH1 (0.60) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7393060 | 0.88 | NAAA (0.48) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11576579 | 0.87 | FOLH1 (0.60) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11545091 | 0.86 | NAAA (0.58) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31344527 | 0.86 | CA1 (0.61) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5856865 | 0.84 | LMNA (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7390854 | 0.84 | KDM4E (0.55) | NAAAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166184-A | 2H-IMIDAZOLE-2-THIONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-08-28 | — | — | US | disclosed |