Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367962 | 0.82 | KDM4E (0.37) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3891785 | 0.80 | MAOB (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL121397 | 0.80 | EGFR (0.41) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL117206 | 0.80 | MAOA (0.38) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL169659 | 0.79 | L3MBTL1 (0.47) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9367601 | 0.77 | MAPK1 (0.40) | TSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3627375 | 0.76 | GSK3B (0.37) | TSHR | |
| SCHEMBL10852424 | 0.76 | MAOB (0.35) | L3MBTL1 | |
| SCHEMBL11958668 | 0.76 | — | — | |
| SCHEMBL10849609 | 0.76 | ALDH1A1 (0.38) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160838-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-07-10 | — | — | US | disclosed |
| US-4079062-A | ANTIMICROBIAL, PLANT GROWTH REGULATORS; 1-(B-ARYL)ETHYL-1H-1,2,4-TRIAZOLE KETALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-03-14 | — | — | US | disclosed |