Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543012 | 0.86 | MAPT (0.40) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL2860220 | 0.78 | KMT2A (0.41) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11545084 | 0.71 | MAPT (0.42) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL7521882 | 0.70 | PIN1 (0.41) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL4728549 | 0.70 | RELA (0.43) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL11072978 | 0.69 | MERTK (0.55) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL30140371 | 0.68 | MAPK1 (0.47) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL2709780 | 0.68 | NT5E (0.60) | MAPTKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL31503831 | 0.68 | MAPK1 (0.50) | MAPTMAPK1KDM4ENPSR1MEN1 | |
| SCHEMBL10981231 | 0.68 | MAPK1 (0.50) | MAPTMAPK1KDM4ENPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |