Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546200 | 0.86 | MAPT (0.41) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL2859335 | 0.79 | KMT2A (0.41) | MAPTKDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL11545084 | 0.70 | MAPT (0.42) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL4728549 | 0.69 | RELA (0.43) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL2710723 | 0.69 | NT5E (0.57) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL2402093 | 0.68 | GPR35 (0.61) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL2567845 | 0.68 | MEN1 (0.42) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15199259 | 0.67 | GPR35 (0.56) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL2711168 | 0.66 | NT5E (0.50) | MAPTKDM4EKMT2ANPSR1MEN1 | |
| SCHEMBL4069709 | 0.66 | TPMT (0.64) | MAPTKDM4EKMT2ANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |