Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546072 | 0.87 | HPGD (0.57) | HPGDLMNARAB9ANLRP3ALDH1A1 | |
| SCHEMBL11549836 | 0.85 | HPGD (0.39) | HPGDLMNARAB9ANLRP3ALDH1A1 | |
| SCHEMBL11545759 | 0.84 | SMN1; SMN2 (0.41) | HPGDLMNARAB9ANLRP3ALDH1A1 | |
| SCHEMBL11545231 | 0.83 | NLRP3 (0.52) | HPGDLMNARAB9ANLRP3ALDH1A1 | |
| SCHEMBL11548757 | 0.76 | BACE1 (0.56) | LMNARAB9AALDH1A1TSHRNPSR1 | |
| SCHEMBL11546761 | 0.76 | ALDH1A1 (0.40) | HPGDLMNARAB9AALDH1A1TSHR | |
| SCHEMBL11046716 | 0.74 | NLRP3 (0.44) | HPGDRAB9ANLRP3ALDH1A1TSHR | |
| SCHEMBL11547093 | 0.74 | HPGD (0.48) | HPGDLMNARAB9ATSHRCSNK2A2 | |
| SCHEMBL11547363 | 0.73 | LMNA (0.52) | LMNATSHRKDM4ESMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL11547356 | 0.72 | LMNA (0.53) | LMNATSHRKDM4ESMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |