Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545180 | 0.88 | PRCP (0.34) | PRCPDPP4DPP8DPP7 | |
| SCHEMBL11549946 | 0.84 | PRCP (0.33) | PRCPDPP7 | |
| SCHEMBL7376051 | 0.82 | PRCP (0.34) | PRCPDPP4DPP8DPP7 | |
| SCHEMBL11618241 | 0.82 | PRCP (0.38) | ALDH1A1PRCPDPP4DPP8TDP1 | |
| SCHEMBL11545563 | 0.81 | PRCP (0.33) | PRCPDPP7 | |
| SCHEMBL11549357 | 0.79 | PRCP (0.39) | PRCPDPP4KDM4EDPP7 | |
| SCHEMBL11546116 | 0.79 | MEN1 (0.39) | ALDH1A1PRCPDPP4DPP8KDM4E | |
| SCHEMBL23039193 | 0.77 | PRCP (0.35) | PRCPDPP4DPP8DPP7 | |
| SCHEMBL599792 | 0.77 | ALDH1A1 (0.45) | ALDH1A1PRCPDPP4DPP8DPP7 | |
| SCHEMBL542283 | 0.77 | NOS2 (0.39) | PRCPDPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |