SCHEMBL599792

SCHEMBL599792

CCCC(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
PRCP P42785 3/20 0.44
DPP7 Q9UHL4 2/20 0.40
TLR2 O60603 2/20 0.38
ELANE P08246 1/20 0.35
NOS2 P35228 2/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
DPP4 P27487 3/20 0.34
DPP8 Q6V1X1 2/20 0.33
DPP9 Q86TI2 2/20 0.33
SCN4A P35499 1/20 0.33
FAP Q12884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742919 0.90 PRCP (0.49) ALDH1A1PRCPDPP7TLR2NOS2
SCHEMBL542283 0.90 NOS2 (0.39) PRCPDPP7ELANENOS2NOS3
SCHEMBL5600789 0.89 PRCP (0.51) PRCPDPP7TLR2
SCHEMBL30265157 0.88 PRCP (0.44) PRCPDPP7TLR2ELANENOS2
SCHEMBL9362980 0.88 PRCP (0.44) PRCPDPP7TLR2ELANENOS2
SCHEMBL15648704 0.88 PRCP (0.54) PRCPDPP7TLR2
SCHEMBL15649396 0.88 PRCP (0.54) PRCPDPP7TLR2
SCHEMBL13278868 0.88 PRCP (0.54) PRCPDPP7TLR2
SCHEMBL17203961 0.88 PRCP (0.54) PRCPDPP7TLR2
SCHEMBL30103314 0.88 PRCP (0.50) PRCPDPP7TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948199-B1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LAB INC (US) 2015-08-12 EP disclosed
EP-1960415-B1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LAB INC (US) 2015-03-04 EP disclosed
CN-102534864-B Preparation method of alkylation chitosan fiber UNIV QINGDAO SCIENCE & TECHNOLOGY 2013-10-16 CN disclosed
US-8293253-B2 Compositions for controlled delivery of pharmaceutically active compounds IDEXX LABORATORIES, INC. (US) 2012-10-23 US disclosed
CN-102534864-A Preparation method of alkylation chitosan fiber UNIV QINGDAO SCIENCE & TECHNOLOGY 2012-07-04 CN disclosed
US-8114440-B2 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. (US) 2012-02-14 US disclosed
US-8017159-B2 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LABORATORIES, INC. (US) 2011-09-13 US disclosed
US-20100240741-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LABORATORIES, INC. (US) 2010-09-23 US disclosed
US-20100204303-A1 Pharmaceutical Compositions for Administering Oligonucleotides IDEXX LABORATORIES, INC. (US) 2010-08-12 US disclosed
US-7754679-B2 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES, INC. (US) 2010-07-13 US disclosed
WO-2007058800-A2 PHOSPHOLIPID GEL COMPOSITIONS FOR DELIVERY OF APTAMERS AND METHODS OF TREATING CONDITIONS USING SAME IDEXX LABORATORIES INC. (US) 2007-05-24 WO disclosed
WO-2007058801-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS IDEXX LABORATORIES INC. (US) 2007-05-24 WO disclosed
US-20070110827-A1 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. 2007-05-17 US disclosed
US-20070110775-A1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same IDEXX LABORATORIES INC. 2007-05-17 US disclosed
US-20070111969-A1 Pharmaceutical compositions for the administration of aptamers IDEXX LABORATORIES INC. 2007-05-17 US disclosed
WO-2006050002-A2 COMPOSITIONS FOR CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS IDEXX LABORATORIES, INC. (US) 2006-05-11 WO disclosed
US-20060093632-A1 Compositions for controlled delivery of pharmaceutically active compounds IDEXX LABORATORIES, INC. 2006-05-04 US disclosed
EP-0240554-A1 TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD RAJADHYAKSHA, Vithal J. (US) 1987-10-14 EP disclosed
WO-1987001935-A1 TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD RAJADHYAKSHA VITHAL J 1987-04-09 WO disclosed
EP-0010347-B1 NOVEL SUBSTITUTED OMEGA-AROYL(PROPIONYL OR BUTYRYL)-L-PROLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION AMERICAN CYANAMID COMPANY (US) 1983-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060093632-A1 Compositions for controlled delivery of pharmaceutically active compounds LIPA, CEL, LPXN ALDH1A1 1640/4885PRCP 131/4885DPP7 385/4885
US-20100240741-A1 PHARMACEUTICAL COMPOSITIONS FOR THE ADMINISTRATION OF APTAMERS PHOSPHO1, SGMS1, PCYT1A ALDH1A1 4408/4885PRCP 706/4885DPP7 1303/4885
US-20070111969-A1 Pharmaceutical compositions for the administration of aptamers PHOSPHO1, SGMS1, PCYT1A ALDH1A1 4408/4885PRCP 706/4885DPP7 1303/4885
US-20100204303-A1 Pharmaceutical Compositions for Administering Oligonucleotides SLCO2A1, SLCO1A2, SLCO2B1 ALDH1A1 2454/4885PRCP 1472/4885DPP7 2642/4885
US-20070110827-A1 Pharmaceutical compositions for the administration of aptamers PHOSPHO1, SGMS1, PCYT1A ALDH1A1 4408/4885PRCP 706/4885DPP7 1303/4885
US-20070110775-A1 Phospholipid gel compositions for delivery of aptamers and methods of treating conditions using same ANXA6, ANXA2, PLTP ALDH1A1 3745/4885PRCP 1380/4885DPP7 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.