Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550432 | 0.83 | OPRM1 (0.42) | OPRM1TP53SPHK1LAP3GRIK1 | |
| SCHEMBL11550427 | 0.82 | OPRM1 (0.48) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL11303488 | 0.81 | OPRM1 (0.56) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL28092875 | 0.80 | OPRM1 (0.55) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL11300888 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL11300003 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL9193047 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL9295913 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL1794453 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 | |
| SCHEMBL1793159 | 0.79 | OPRM1 (0.54) | OPRM1TP53LMNASPHK1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134842-A | Molded plastic bearing assembly | KAMATICS CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4053665-A | MOLDED PLASTIC BEARING ASSEMBLY | KAMATICS CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-3996143-A | Cured acrylate bearing member | KAMATICS CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |