Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547263 | 0.83 | OPRM1 (0.52) | OPRM1SPHK1TP53GRIK1SLC1A2 | |
| SCHEMBL11550427 | 0.81 | OPRM1 (0.48) | OPRM1SPHK1TP53GRIK1SLC1A2 | |
| SCHEMBL28092875 | 0.76 | OPRM1 (0.55) | OPRM1SPHK1TP53GRIK1SLC1A2 | |
| SCHEMBL16599683 | 0.75 | OPRM1 (0.44) | OPRM1SPHK1DNM1TP53MEN1 | |
| SCHEMBL17099471 | 0.75 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27221680 | 0.74 | OPRM1 (0.52) | OPRM1SPHK1DNM1TP53TSHR | |
| SCHEMBL3694779 | 0.74 | OPRM1 (0.52) | OPRM1SPHK1DNM1TP53TSHR | |
| SCHEMBL17846805 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL28458489 | 0.74 | OPRM1 (0.52) | OPRM1SPHK1DNM1TP53TSHR | |
| SCHEMBL6677962 | 0.73 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134842-A | Molded plastic bearing assembly | KAMATICS CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4053665-A | MOLDED PLASTIC BEARING ASSEMBLY | KAMATICS CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4048370-A | Shaped bearing member | KAMATICS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-3996143-A | Cured acrylate bearing member | KAMATICS CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |