Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 8/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580521 | 0.86 | LMNA (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11665344 | 0.86 | SMN1; SMN2 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9799480 | 0.84 | SMN1; SMN2 (0.46) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4280447 | 0.84 | HTT (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4275163 | 0.84 | HTT (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4275686 | 0.84 | HTT (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4271921 | 0.84 | HTT (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4279420 | 0.84 | HTT (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL10613666 | 0.82 | TSHR (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL27372349 | 0.82 | ACHE (0.42) | THRBACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134842-A | Molded plastic bearing assembly | KAMATICS CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4053665-A | MOLDED PLASTIC BEARING ASSEMBLY | KAMATICS CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4048370-A | Shaped bearing member | KAMATICS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-3996143-A | Cured acrylate bearing member | KAMATICS CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |