Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545883 | 0.79 | SLC18A3 (0.39) | SLC6A3SLC6A2TAAR1ADRA1AKDM1A | |
| SCHEMBL11828815 | 0.76 | — | — | |
| SCHEMBL10506401 | 0.73 | HTR3A (0.46) | SLC6A3SLC6A2HTR3ASLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL10677950 | 0.72 | HTR3A (0.44) | SLC6A3SLC6A2HTR3ASLC6A4ADRA1A | |
| SCHEMBL11829118 | 0.69 | CA12 (0.45) | LMNA | |
| SCHEMBL28289382 | 0.67 | HTR3A (0.57) | SLC6A3SLC6A2HTR3ASLC6A4ADRA1A | |
| SCHEMBL6779675 | 0.67 | HTR3A (0.69) | SLC6A3SLC6A2HTR3ASLC6A4HTT | |
| SCHEMBL12647379 | 0.67 | KDM1A (0.47) | KDM1ALMNA | |
| SCHEMBL23337648 | 0.65 | TAAR1 (0.50) | SLC6A3SLC6A2HTR3ATAAR1SLC6A4 | |
| SCHEMBL13458285 | 0.65 | NPC1 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163857-A | DRUGS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-08-07 | — | — | US | disclosed |