Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | MAOA | P21397 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734079 | 0.81 | CYP1A2 (0.34) | CYP2C19CYP1A2LMNAHSD17B10 | |
| SCHEMBL11547375 | 0.79 | SLC6A3 (0.44) | TAAR1MAOBKDM1ALMNASLC6A2 | |
| SCHEMBL11094591 | 0.79 | SLC18A3 (0.41) | SLC18A3SIGMAR1TAAR1MAOBMAOA | |
| SCHEMBL13458285 | 0.79 | NPC1 (0.44) | LMNAHTR2C | |
| SCHEMBL14044884 | 0.77 | DRD3 (0.46) | KDM1ALMNACYP3A4HTR2CDRD3 | |
| SCHEMBL12647379 | 0.77 | KDM1A (0.47) | KDM1ALMNAHTR2CRCOR1 | |
| SCHEMBL11828815 | 0.75 | — | — | |
| SCHEMBL4559809 | 0.75 | CYP11B2 (0.38) | KDM1ACYP2A6KCNH2 | |
| SCHEMBL11835500 | 0.75 | ALDH1A1 (0.35) | CYP2A6CYP2A13HSD17B10 | |
| SCHEMBL11286867 | 0.74 | MAOB (0.38) | TAAR1MAOBMAOAKDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311903-A | Cyclic annular 3- phenyl tetramic acid derivatives with herbicide effect | 拜耳作物科学股份公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-3194406-A1 | TRICYCLIC HETEROCYCLES FOR USE AS BET PROTEIN INHIBITORS | Incyte Holdings Corporation (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044130-A1 | TRICYCLIC HETEROCYCLES FOR USE AS BET PROTEIN INHIBITORS | INCYTE CORPORATION (US) | 2016-03-24 | — | — | WO | disclosed |
| CN-1004272-B | PYRAZOLINE INSECTICIDES | FMC公司 | 1989-05-24 | — | — | CN | disclosed |
| US-4163857-A | DRUGS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-08-07 | — | — | US | disclosed |
| US-4105765-A | ANTITHROMBOTICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4058616-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-11-15 | — | — | US | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |