Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544018 | 0.72 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP4F2 | |
| SCHEMBL11547281 | 0.72 | ATM (0.42) | ATMALDH1A1SOAT1LMNAPOLB | |
| SCHEMBL17904756 | 0.70 | LMNA (0.40) | PPM1BPTPN1PPP1CCALDH1A1CYP4F2 | |
| SCHEMBL13085057 | 0.70 | LMNA (0.40) | PPM1BPTPN1PPP1CCALDH1A1CYP4F2 | |
| SCHEMBL11486818 | 0.70 | ALDH1A1 (0.33) | ATMPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL11484005 | 0.70 | ATM (0.33) | ATMPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL9856940 | 0.69 | ALDH1A1 (0.46) | ATMALDH1A1SOAT1LMNAPOLB | |
| SCHEMBL12966496 | 0.69 | — | — | |
| SCHEMBL3039889 | 0.69 | — | — | |
| SCHEMBL563498 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158635-A | Detergent formulations containing tetrahydropyran or 1,4-dioxane polycarboxylates and method for using same | MONSANTO COMPANY (US) | 1979-06-19 | — | — | US | disclosed |
| US-4134902-A | DETERGENT BUILDERS, CALCIUM AND MAGNESIUM SEQUESTRANTS, SCALE DISSOLVERS | MONSANTO COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4102903-A | DETERGENTS BUILDERS, SEQUESTERING AGENTS | MONSANTO COMPANY (US) | 1978-07-25 | — | — | US | disclosed |