Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21063744 | 0.85 | ALDH1A1 (0.36) | NOTUMKDM4EALDH1A1KMT2AKDM2B | |
| SCHEMBL21098492 | 0.81 | KDM4E (0.32) | KDM4EALDH1A1KMT2ADRD2DRD4 | |
| SCHEMBL15536106 | 0.76 | KDM2B (0.38) | NOTUMDRD2DRD4DRD3GAA | |
| SCHEMBL28200636 | 0.69 | ALDH1A1 (0.39) | NOTUMKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3463544 | 0.69 | CA12 (0.44) | NOTUMKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL4773772 | 0.69 | ALDH1A1 (0.39) | NOTUMKDM4EALDH1A1KMT2AALOX15 | |
| SCHEMBL24036232 | 0.69 | HCAR3 (0.41) | KDM4EALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL10208596 | 0.67 | KDM4E (0.48) | NOTUMKDM4EALDH1A1KMT2ATOP2A | |
| SCHEMBL8638685 | 0.66 | KDM4E (0.38) | NOTUMKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10996179 | 0.65 | KDM4E (0.46) | KDM4EALDH1A1KMT2ATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004279-A1 | Process for the preparation of 4-pyridone-3-carboxylic acids, 1-cyclopropyl-4-pyridone-3-carboxylic acid derivatives and medicines containing them | BAYER AG (DE) | 1979-10-03 | — | — | EP | disclosed |