Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019137 | 0.86 | KDM5A (0.38) | KDM4ETYRDOHHKMT2ALMNA | |
| SCHEMBL4773904 | 0.77 | CA12 (0.43) | KDM4ETYRDOHHKMT2ACA12 | |
| SCHEMBL3463544 | 0.75 | CA12 (0.44) | KDM4EDOHHKMT2ALMNAPKM | |
| SCHEMBL969727 | 0.75 | AKR1B1 (0.46) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL4773772 | 0.75 | ALDH1A1 (0.39) | KDM4ETYRDOHHKMT2ALMNA | |
| SCHEMBL28200636 | 0.75 | ALDH1A1 (0.39) | KDM4ETYRDOHHKMT2ALMNA | |
| SCHEMBL15333147 | 0.74 | NPC1 (0.45) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL969676 | 0.71 | NOTUM (0.39) | KDM4EKMT2ALMNAMEN1ABCC4 | |
| SCHEMBL4770346 | 0.70 | CPB2 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL21098141 | 0.70 | ALDH1A1 (0.39) | KDM4EKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111433206-B | Compounds of formula (I) | 葛兰素史克知识产权开发有限公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-0855183-A2 | Manufacture of taste-masked preparations of antibacterial quinolone derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-29 | — | — | EP | disclosed |
| CN-1188646-A | Preparation of concealed taste preparations of antibucterially active quinlone derivatives | HOECHST AG (DE) | 1998-07-29 | — | — | CN | disclosed |
| US-4621088-A | N-acyl derivatives of amino acids and their esters, and drugs in which they are present | PANMEDICA (FR) | 1986-11-04 | — | — | US | disclosed |
| US-4291035-A | SHOW A SYNERGISTIC EFFECT IN THE TREATMENT OF BACTERIAL INFECTIONS OF THE URINARY TRACT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1981-09-22 | — | — | US | disclosed |
| US-4291035-A | SHOW A SYNERGISTIC EFFECT IN THE TREATMENT OF BACTERIAL INFECTIONS OF THE URINARY TRACT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1981-09-22 | — | — | US | disclosed |
| US-4291035-A | SHOW A SYNERGISTIC EFFECT IN THE TREATMENT OF BACTERIAL INFECTIONS OF THE URINARY TRACT | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1981-09-22 | — | — | US | disclosed |