Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549447 | 0.85 | CES1 (0.41) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11540824 | 0.85 | CES1 (0.51) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL11543720 | 0.84 | CES1 (0.40) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL868096 | 0.83 | CES1 (0.51) | CES1CES2SRCLMNATSHR | |
| SCHEMBL11540703 | 0.81 | CES1 (0.38) | CES1PTPN1SMN1; SMN2POLBSRC | |
| SCHEMBL6885914 | 0.78 | CES1 (0.44) | CES1PTPN1SMN1; SMN2POLBCES2 | |
| SCHEMBL11543025 | 0.77 | NPC1 (0.37) | CES1PTPN1SMN1; SMN2POLBCES2 | |
| SCHEMBL10456740 | 0.75 | CES1 (0.59) | CES1POLBCES2SRCLMNA | |
| SCHEMBL7911425 | 0.74 | CES1 (0.49) | CES1CES2SRCLMNACTNNB1 | |
| SCHEMBL11548159 | 0.73 | CES1 (0.47) | CES1PTPN1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |