Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540824 | 0.87 | CES1 (0.51) | CES1PTPN1TSHR | |
| SCHEMBL11545782 | 0.80 | CES1 (0.49) | CES1PTPN1CETPTSHR | |
| SCHEMBL11544661 | 0.79 | CES1 (0.54) | CES1PTPN1TSHRPRSS1CTSG | |
| SCHEMBL11547246 | 0.75 | CES1 (0.43) | CES1PTPN1CETPNAAAKIF11 | |
| SCHEMBL11549447 | 0.74 | CES1 (0.41) | CES1PTPN1KIF11TSHR | |
| SCHEMBL11543720 | 0.73 | CES1 (0.40) | CES1PTPN1TSHRPRSS1CTSG | |
| SCHEMBL11547495 | 0.73 | CES1 (0.40) | CES1PTPN1CES2TSHR | |
| SCHEMBL11541059 | 0.73 | ALDH1A1 (0.45) | PTPN1CETPTSHRPRSS1CTSG | |
| SCHEMBL11171387 | 0.72 | CES1 (0.58) | CES1NAAACES2TSHR | |
| SCHEMBL1260547 | 0.72 | CES1 (0.46) | CES1NAAAKIF11CES2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160794-A | CURING OR POLYMERIZATION PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4082821-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |