Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582887 | 0.89 | TDP1 (0.46) | HTR2CHTR2BCTSCELANETSHR | |
| SCHEMBL11549982 | 0.85 | HTR2C (0.42) | HTR2CHTR2BCTSCTSHRTAAR1 | |
| SCHEMBL7386495 | 0.84 | CYP2C19 (0.42) | HTR2CHTR2BCTSCELANEGBA1 | |
| SCHEMBL11545881 | 0.83 | IDO1 (0.43) | HTR2CHTR2BCTSCELANEKDM4E | |
| SCHEMBL7379917 | 0.81 | KMT2A (0.42) | HTR2CHTR2BCTSCELANEKDM4E | |
| SCHEMBL7373953 | 0.81 | KMT2A (0.42) | HTR2CHTR2BCTSCELANEKDM4E | |
| SCHEMBL474619 | 0.81 | HTR2C (0.47) | HTR2CHTR2BCTSCELANETSHR | |
| SCHEMBL11544707 | 0.80 | SLC6A1 (0.41) | HTR2CHTR2BCTSCELANEKDM4E | |
| SCHEMBL28274418 | 0.80 | HTR2C (0.46) | HTR2CHTR2BCTSCELANETSHR | |
| SCHEMBL11544261 | 0.79 | ELANE (0.38) | HTR2CHTR2BCTSCELANETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |