Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11544005 | 0.99 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3PLD1 | |
| SCHEMBL16654410 | 0.84 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL16651907 | 0.83 | HTR1A (0.50) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL11547851 | 0.82 | LTA4H (0.62) | HTR1ASLC6A2SLC6A4SLC6A3PLD1 | |
| SCHEMBL11545028 | 0.75 | LTA4H (0.63) | HTR1APLD1SCN9ALTA4HHTR6 | |
| SCHEMBL1594249 | 0.75 | PLD1 (0.53) | HTR1ASLC6A4PLD1HRH3HTR6 | |
| SCHEMBL2224435 | 0.74 | ADRB1 (0.57) | HTR1APLD1HRH3HTR6 | |
| SCHEMBL11545709 | 0.74 | HTR2C (0.51) | HTR1ASLC6A4SCN9ALTA4HHTR6 | |
| Hydrochloric Acid SCHEMBL26633229 | 0.74 | PLD1 (0.51) | HTR1ASLC6A4PLD1HRH3HTR6 | |
| Hydrochloric Acid SCHEMBL20140251 | 0.74 | PLD1 (0.51) | HTR1ASLC6A4PLD1HRH3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |