Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092049 | 0.86 | PLK1 (0.62) | GABRA5BAZ2BMAPTOPRM1OPRD1 | |
| SCHEMBL23834894 | 0.86 | GABRA5 (0.52) | GABRA5BAZ2BMAPTOPRM1OPRD1 | |
| SCHEMBL4843142 | 0.83 | MAPK1 (0.54) | GABRA5MAPTNNMT | |
| SCHEMBL1091622 | 0.83 | MAPT (0.68) | GABRA5BAZ2BMAPTOPRM1OPRD1 | |
| SCHEMBL15647035 | 0.81 | GABRA5 (0.50) | GABRA5BAZ2BMAPTOPRM1OPRD1 | |
| SCHEMBL11551255 | 0.81 | NNMT (0.62) | MAPTOPRM1OPRD1NNMT | |
| SCHEMBL14516103 | 0.79 | NNMT (0.64) | GABRA5BAZ2BMAPTOPRM1OPRD1 | |
| SCHEMBL13702416 | 0.78 | L3MBTL1 (0.68) | GABRA5MAPTEPHX2 | |
| Hydrochloric Acid SCHEMBL12502696 | 0.76 | PLK1 (0.71) | MAPTPLK1 | |
| SCHEMBL13702364 | 0.75 | CD274 (0.53) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |