Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728398 | 0.80 | MEN1 (0.47) | POLBRAD52MAPTGSK3BESR1 | |
| SCHEMBL6157510 | 0.79 | ESR1 (0.63) | MAPTGSK3BESR1PGRHTR1A | |
| SCHEMBL11550294 | 0.79 | MEN1 (0.48) | POLBRAD52MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11547653 | 0.78 | HSP90AA1 (0.49) | POLBRAD52MAPTMEN1KMT2A | |
| Phosphoric Acid SCHEMBL11545454 | 0.77 | RAD52 (0.50) | POLBRAD52MAPTGSK3BESR1 | |
| SCHEMBL5496134 | 0.76 | MAOA (0.60) | RAD52GSK3BMEN1KMT2AHSP90AA1 | |
| SCHEMBL11543929 | 0.73 | NSD2 (0.62) | POLBRAD52MAPTHTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL11544270 | 0.72 | HSP90AA1 (0.67) | POLBRAD52MAPTESR1PGR | |
| SCHEMBL8660088 | 0.72 | ESR1 (0.55) | POLBMAPTGSK3BESR1PGR | |
| SCHEMBL11544850 | 0.64 | MAOA (0.47) | GSK3BMAOAMAOBL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |