Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543503 | 0.89 | L3MBTL1 (0.51) | HNF4AHPRT1ALDH1A1KDM4EMAPT | |
| SCHEMBL10755667 | 0.85 | RXRA (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11457217 | 0.83 | MEN1 (0.46) | HNF4AALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL10760681 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EERAP1MAPTCYP3A4 | |
| SCHEMBL11743159 | 0.82 | ALDH1A1 (0.57) | HNF4AALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL10762730 | 0.82 | MAPK1 (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7274704 | 0.82 | MAPT (0.46) | HNF4AALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL11626335 | 0.81 | TTR (0.49) | MAPTTP53MEN1KMT2ANPC1 | |
| SCHEMBL11637588 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ERAP1MAPTMEN1KMT2A | |
| SCHEMBL11548743 | 0.79 | MAPT (0.48) | HNF4AALDH1A1KDM4EMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141990-A | BACTERICIDES, FUNGICIDES | RIKER LABORATORIES, INC. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4022908-A | Use of certain 2-nitro-3-phenyl-alkoxybenzofurans in inhibiting growth of microorganisms and intermediates in the synthesis of said benzofurans | RIKER LABORATORIES, INC. (US) | 1977-05-10 | — | — | US | disclosed |