Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26031131 | 0.83 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6322151 | 0.83 | ADRB1 (0.67) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6322149 | 0.83 | ADRB1 (0.67) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL26031128 | 0.83 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL26031129 | 0.83 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL21759057 | 0.83 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11151410 | 0.81 | TSHR (0.52) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9567084 | 0.81 | ADRB2 (0.49) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11821804 | 0.79 | ADRB2 (0.46) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL893963 | 0.78 | BCHE (0.63) | MEN1KMT2ADNM1BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |