Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547925 | 0.81 | ADRB2 (0.50) | ADRB2ADRB1ADRB3ACHEMEN1 | |
| SCHEMBL9567153 | 0.79 | CA1 (0.50) | KMT2ACYP1A2CYP2D6CYP3A4KCNH2 | |
| SCHEMBL11145485 | 0.77 | ADRB2 (0.62) | ADRB2ADRB1ADRB3ABCB1LMNA | |
| SCHEMBL11151410 | 0.77 | TSHR (0.52) | ADRB2ADRB1ADRB3ACHEMEN1 | |
| SCHEMBL4959042 | 0.77 | CA1 (0.45) | KMT2ACYP1A2CYP2D6CYP3A4TSHR | |
| SCHEMBL11534685 | 0.76 | NR2E1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6322151 | 0.76 | ADRB1 (0.67) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL26031128 | 0.76 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL21759057 | 0.76 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL26031131 | 0.76 | ADRB1 (0.64) | ADRB2ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559285-A1 | 1,4-Dioxino 2,3-b pyridine derivatives having serotonergic activity | Akzo Nobel N.V. (NL) | 1993-09-08 | — | — | EP | disclosed |