SCHEMBL11548141

SCHEMBL11548141

CCOC=Nc1ccc(C(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
SLC22A3 O75751 1/20 0.40
ACHE P22303 9/20 0.36
BCHE P06276 8/20 0.36
PTGS2 P35354 2/20 0.36
TSHR P16473 1/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11548138 1.00 CA1 (0.41) CA1CA2SLC22A2SLC22A1SLC22A3
SCHEMBL13567566 0.79 CA1 (0.47) CA1CA2SLC22A2SLC22A1SLC22A3
SCHEMBL11547155 0.79 CYP2D6 (0.44) CA2SLC22A2SLC22A1SLC22A3ACHE
SCHEMBL8585835 0.77 PTGS2 (0.53) CA1CA2PTGS2LMNA
SCHEMBL8595189 0.77 PTGS2 (0.37) CA1CA2SLC22A2SLC22A1SLC22A3
SCHEMBL14925518 0.76 PTGS2 (0.50) PTGS2HPGDSMN1; SMN2
SCHEMBL4361001 0.76 PTGS2 (0.50) PTGS2HPGDSMN1; SMN2
SCHEMBL4361000 0.76 PTGS2 (0.50) PTGS2HPGDSMN1; SMN2
SCHEMBL6199076 0.76 S100B (0.46) CA1CA2ACHEPTGS2TSHR
SCHEMBL6199068 0.76 S100B (0.46) CA1CA2ACHEPTGS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4152348-A INHIBITION OF COLOR FORMATION ON STORAGE THE UPJOHN COMPANY (US) 1979-05-01 US disclosed
US-4152349-A IMPROVED REACTIVITY, STORAGE STABILITY THE UPJOHN COMPANY (US) 1979-05-01 US disclosed
US-4097599-A PESTICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1978-06-27 US disclosed
US-4038405-A MITICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1977-07-26 US disclosed