Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101485 | 0.71 | CARM1 (0.45) | CARM1PRMT6ALDH1A1NPSR1TDP1 | |
| SCHEMBL155410 | 0.69 | RIPK1 (0.54) | ALDH1A1KDM4ECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19936019 | 0.68 | — | — | |
| SCHEMBL6928868 | 0.66 | CHRNB4 (0.50) | CARM1PRMT6ALDH1A1NPSR1TDP1 | |
| SCHEMBL6928871 | 0.66 | CHRNB4 (0.50) | CARM1PRMT6ALDH1A1NPSR1TDP1 | |
| SCHEMBL7149882 | 0.64 | CCR3 (0.40) | CARM1PRMT6 | |
| SCHEMBL2674960 | 0.64 | POLB (0.68) | CARM1PRMT6KDM4E | |
| SCHEMBL12049585 | 0.63 | CARM1 (0.49) | CARM1PRMT6ALDH1A1NPSR1TDP1 | |
| SCHEMBL7339018 | 0.63 | CARM1 (0.49) | CARM1PRMT6ALDH1A1NPSR1TDP1 | |
| SCHEMBL11772305 | 0.62 | MEN1 (0.41) | ALDH1A1NPSR1TDP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |