Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468240 | 0.72 | MGLL (0.40) | CCR3 | |
| SCHEMBL1831035 | 0.71 | CCR3 (0.46) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL15586710 | 0.70 | — | — | |
| SCHEMBL155410 | 0.69 | RIPK1 (0.54) | — | |
| SCHEMBL903058 | 0.69 | ABCB1 (0.47) | — | |
| SCHEMBL11572447 | 0.69 | ABCB1 (0.47) | — | |
| SCHEMBL327856 | 0.68 | CCR3 (0.66) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL3436965 | 0.67 | PRMT6 (0.62) | CCR3CARM1PRMT6PRMT3PRMT1 | |
| SCHEMBL16707757 | 0.67 | MC4R (0.49) | CCR3MC4R | |
| SCHEMBL9025379 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6524571-B1 | Insertion of a methioninase gene into tumor cells, optionally in combination with administration of methioninase, methionine deprivation or administration of a chemotherapeutic agent, retrovirus or adenovirus | ANTICANCER, INC. | 2003-02-25 | — | — | US | disclosed |
| EP-1133567-A1 | METHIONINASE GENE THERAPY FOR TUMOR TREATMENT | ANTICANCER, INC. (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000029589-A9 | METHIONINASE GENE THERAPY FOR TUMOR TREATMENT | ANTICANCER INC (US) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000029589-A1 | METHIONINASE GENE THERAPY FOR TUMOR TREATMENT | ANTICANCER, INC. (US) | 2000-05-25 | — | — | WO | disclosed |