Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759583 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1GAAPKMPARP1 | |
| SCHEMBL11088552 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1GAAPKMGLA | |
| SCHEMBL28663365 | 0.76 | ALPG (0.48) | KDM4EALDH1A1GAAPKMGLA | |
| SCHEMBL11547459 | 0.76 | SMN1; SMN2 (0.47) | KDM4EALDH1A1GAAPKMPARP1 | |
| SCHEMBL11549158 | 0.75 | KDM4E (0.74) | KDM4EALDH1A1GAAPARP1GLA | |
| SCHEMBL11266270 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1GAAPKMGLA | |
| SCHEMBL28351806 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1GAAGLASMN1; SMN2 | |
| SCHEMBL28355634 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1GAAGLASMN1; SMN2 | |
| SCHEMBL11546934 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAPKMPARP1 | |
| SCHEMBL11357153 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1GAAPKMGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132851-A | Process for producing quinazolone derivatives | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1979-01-02 | — | — | US | disclosed |