SCHEMBL11548264

SCHEMBL11548264

O=Nc1ccc(Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
HSD17B10 Q99714 3/20 0.65
CYP3A4 P08684 2/20 0.65
TSHR P16473 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
HTT P42858 1/20 0.65
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
MAPT P10636 1/20 0.39
MT-CO2 P00403 1/20 0.39
NPC1 O15118 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
SCN9A Q15858 1/20 0.38
CES1 P23141 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85600 0.85
SCHEMBL9225044 0.81 ALDH1A1 (0.63) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL9516529 0.80 LMNA (0.57) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL1686571 0.80 LMNA (0.57) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL9222866 0.79 ALDH1A1 (0.57) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL9223214 0.79 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL655572 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL9221118 0.77 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL5685218 0.77 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRTDP1
SCHEMBL10866233 0.77 ALDH1A1 (0.95) ALDH1A1HSD17B10CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993086-B2 Recordable optical recording medium TAIYO YUDEN CO., LTD. (JP) 2015-03-31 US disclosed
US-4163015-A ANTIBACTERIAL AGENTS STERLING DRUG INC. (US) 1979-07-31 US disclosed
US-4138405-A BACTERICIDES STERLING DRUG INC. (US) 1979-02-06 US disclosed