SCHEMBL1686571

SCHEMBL1686571

Clc1ccc(Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
MAPT P10636 2/20 0.52
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 2/20 0.50
SLC6A2 P23975 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
PTGS1 P23219 1/20 0.50
MAPK1 P28482 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SCN9A Q15858 2/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516529 1.00 LMNA (0.57) LMNACYP2A6MAPTALDH1A1ALOX15
SCHEMBL9479942 0.88 ALDH1A1 (0.72) LMNAMAPTALDH1A1ALOX15SLC6A2
SCHEMBL1118626 0.88 ALDH1A1 (0.72) LMNAMAPTALDH1A1ALOX15SLC6A2
SCHEMBL6710729 0.86 MAPT (0.43) LMNACYP2A6MAPTALDH1A1ALOX15
SCHEMBL11156115 0.86 GSK3B (0.53) LMNAMAPTALDH1A1ALOX15TDP1
SCHEMBL23734739 0.86 IDO1 (0.68) LMNACYP2A6MAPTALDH1A1ALOX15
SCHEMBL2778029 0.86 MAPT (0.61) MAPTALDH1A1ALOX15SLC6A2HSD17B10
SCHEMBL11582160 0.86 HPGD (0.61) LMNAMAPTALDH1A1TDP1PTGS2
SCHEMBL5542327 0.84 MAPT (0.42) LMNACYP2A6MAPTALDH1A1ALOX15
SCHEMBL10570649 0.84 KMT2A (0.61) LMNAMAPTALDH1A1PTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752257-A Waterproof alkali-resistant exterior wall paint and preparation method thereof 广东米奇涂料有限公司 2025-04-04 CN claimed
CN-114907230-B Organic soft porous frame material and preparation method and application thereof 北京化工大学 2023-02-28 CN claimed
CN-114907230-A Organic soft porous frame material and preparation method and application thereof 北京化工大学 2022-08-16 CN claimed
US-5541032-A CHARGE STABILIZERS WHICH ARE INSENSITIVE TO MOISTURE, HEAT RESISTANT AND PRODUCE CRISP, UNIFORM VISIBLE IMAGES OF HIGH COLOR INTENSITY BASF AKTIENGESELLSCHAFT (DE) 1996-07-30 US claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
CN-119752257-A Waterproof alkali-resistant exterior wall paint and preparation method thereof 广东米奇涂料有限公司 2025-04-04 CN disclosed
CN-119752257-A Waterproof alkali-resistant exterior wall paint and preparation method thereof 广东米奇涂料有限公司 2025-04-04 CN disclosed
CN-119080809-A Anthracene-based derivative based on boron-nitrogen multiple resonance skeleton, preparation and application thereof 华中科技大学 2024-12-06 CN disclosed
CN-118843615-A Dicarbazole compound and organic electroluminescent element 国立大学法人京都大学 2024-10-25 CN disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
US-4413045-A Multilayer electrophotographic photosensitive member comprises disazo charge generator layer, hydrazone transport layer CANON KABUSHIKI KAISHA (JP) 1983-11-01 US disclosed
EP-0016581-A1 Ziegler type catalyst composition EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-10-01 EP disclosed
US-4224182-A POLYMERIZATION CATALYSTS EXXON RESEARCH & ENGINEERING CO. (US) 1980-09-23 US disclosed
US-4218247-A Photoconductive resin containing tertiary amino groups for electrophotography TEIJIN LIMITED (JP) 1980-08-19 US disclosed
US-4176209-A Process for forming polymeric paraxylylene coatings and films possessing improved oxidation resistance RAYTHEON CORPORATION (US) 1979-11-27 US disclosed
US-4144260-A Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4124400-A Flame retardant polymer compositions MONSANTO COMPANY (US) 1978-11-07 US disclosed
US-4082749-A FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST BASF AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 LMNA 1936/4885CYP2A6 1645/4885MAPT 486/4885
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents PNMT, NCL, NPM1 LMNA 167/4885CYP2A6 2928/4885MAPT 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.