SCHEMBL11548272

SCHEMBL11548272

COc1cc(Cl)c(O)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
HSD17B10 Q99714 2/20 0.52
HPGD P15428 1/20 0.52
NPC1 O15118 2/20 0.50
GAA P10253 1/20 0.50
FTO Q9C0B1 1/20 0.49
TAAR1 Q96RJ0 1/20 0.47
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
MAPK1 P28482 2/20 0.44
HSP90AA1 P07900 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
CCR6 P51684 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792597 0.91 NPC1 (0.56) TSHRHSD17B10HPGDNPC1GAA
SCHEMBL11003488 0.88 HTT (0.48) TSHRHSD17B10HPGDHSP90AA1MAOB
SCHEMBL69147 0.86 HSD17B10 (0.52) TSHRHSD17B10HPGDFTOALDH1A1
SCHEMBL4398163 0.86 GAA (0.56) HSD17B10HPGDNPC1GAAFTO
SCHEMBL25664040 0.86 MAOB (0.46) TSHRHSD17B10HPGDNPC1GAA
Chloroneb SCHEMBL22739 0.84 GAA (0.64) TSHRHPGDNPC1GAATAAR1
SCHEMBL248581 0.83 MAOB (0.48) TSHRHSD17B10HPGDNPC1GAA
SCHEMBL13540675 0.82 GAA (0.47) TSHRHSD17B10HPGDNPC1GAA
Methoxymethane SCHEMBL11335592 0.82 HSD17B10 (0.67) TSHRHSD17B10HPGDFTOALDH1A1
SCHEMBL8006836 0.80 NPC1 (0.67) HSD17B10HPGDNPC1GAAFTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117482461-B Fe/Na2SO3Method for efficiently degrading metallocene powder by mechanical grinding agent 浙江工业大学 2025-06-17 CN disclosed
CN-117482461-A Fe/Na 2 SO 3 Method for efficiently degrading metallocene powder by mechanical grinding agent 浙江工业大学 2024-02-02 CN disclosed
US-4137273-A INSECTICIDES, CHEMICAL INTERMEDIATES ZOECON CORPORATION (US) 1979-01-30 US disclosed