SCHEMBL69147

SCHEMBL69147

COc1cc(O)c(Cl)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.52
HPGD P15428 3/20 0.52
TSHR P16473 3/20 0.52
MAOB P27338 1/20 0.46
DPP4 P27487 8/20 0.46
HTT P42858 1/20 0.42
FTO Q9C0B1 1/20 0.42
CYP3A4 P08684 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42
TRPV1 Q8NER1 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
NR1I2 O75469 1/20 0.41
TTR P02766 1/20 0.41
PGR P06401 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25664040 0.91 MAOB (0.46) HSD17B10HPGDTSHRMAOBDPP4
SCHEMBL11003488 0.88 HTT (0.48) HSD17B10HPGDTSHRMAOBDPP4
SCHEMBL248581 0.88 MAOB (0.48) HSD17B10HPGDTSHRMAOBHTT
SCHEMBL11548272 0.86 TSHR (0.52) HSD17B10HPGDTSHRMAOBHTT
SCHEMBL7792597 0.86 NPC1 (0.56) HSD17B10HPGDTSHRMAOBDPP4
SCHEMBL4398163 0.86 GAA (0.56) HSD17B10HPGDMAOBDPP4FTO
SCHEMBL69624 0.84 MAOB (0.59) HSD17B10HPGDTSHRMAOBHTT
Methoxymethane SCHEMBL11335592 0.82 HSD17B10 (0.67) HSD17B10HPGDTSHRFTOCYP3A4
SCHEMBL31144189 0.80 DPP4 (0.46) HSD17B10HPGDTSHRDPP4ALDH1A1
SCHEMBL21611906 0.80 HMGCR (0.41) HSD17B10HPGDTSHRDPP4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-3987109-A POLYMERIZATION OF POLYFUNCTIONAL PHENOLS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885HPGD 3275/4885TSHR 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.