Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.67 |
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CBR1 | P16152 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48305 | 0.87 | HSD17B10 (0.86) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| Methoxymethane SCHEMBL10956939 | 0.85 | HSD17B10 (0.50) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| Methoxymethane SCHEMBL16619761 | 0.82 | HSD17B10 (0.81) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL11548272 | 0.82 | TSHR (0.52) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL69147 | 0.82 | HSD17B10 (0.52) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| 2,4-Dichlorophenol SCHEMBL16619805 | 0.82 | HSD17B10 (0.81) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| Triclofenol SCHEMBL1338 | 0.80 | HSD17B10 (1.00) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL592892 | 0.80 | HSD17B10 (0.75) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| Triclofenol SCHEMBL29387498 | 0.80 | HSD17B10 (1.00) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL11003488 | 0.78 | HTT (0.48) | HSD17B10TSHRHPGDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288147-A | Electro-optical composition of the guest-host type | TIMEX CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4066708-A | PROCESS FOR PREPARING CHLORINATED HYDROQUINONE DIMETHYL ETHERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |