SCHEMBL248581

SCHEMBL248581

COc1cc(Cl)c(Cl)cc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.48
HPGD P15428 3/20 0.48
TSHR P16473 2/20 0.48
HSD17B10 Q99714 1/20 0.48
LCK P06239 1/20 0.44
MAPT P10636 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
TTR P02766 1/20 0.42
PGR P06401 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
HSPA5 P11021 1/20 0.42
CBR1 P16152 1/20 0.42
TBXA2R P21731 1/20 0.42
SLC6A2 P23975 1/20 0.42
AGTR1 P30556 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69147 0.88 HSD17B10 (0.52) MAOBHPGDTSHRHSD17B10MAPT
SCHEMBL4398163 0.88 GAA (0.56) MAOBHPGDHSD17B10MAPTSLC22A6
SCHEMBL25664040 0.88 MAOB (0.46) MAOBHPGDTSHRHSD17B10SLC22A6
SCHEMBL11548272 0.83 TSHR (0.52) MAOBHPGDTSHRHSD17B10MAPT
SCHEMBL2567408 0.82 PTGS2 (0.44) MAOBLCKSLC22A6SLC22A8MEN1
SCHEMBL5572861 0.81 GAA (0.50) HPGDMAPTHSP90AA1MEN1RAB9A
SCHEMBL69624 0.81 MAOB (0.59) MAOBHPGDTSHRHSD17B10MAPT
SCHEMBL11003488 0.80 HTT (0.48) MAOBHPGDTSHRHSD17B10HSP90AA1
SCHEMBL6131942 0.79 TRPV1 (0.43) MAOBTSHRMAPTMEN1KMT2A
SCHEMBL1054210 0.78 ALDH1A1 (0.55) HPGDTSHRALDH1A1AOX1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2670501-A1 REMOVING COMPOUNDS FROM WINE Constellation Brands U.S. Operations, Inc. (US) 2013-12-11 EP claimed
WO-2012106265-A1 REMOVING COMPOUNDS FROM WINE CONSTELLATION WINES U.S., INC. (US) 2012-08-09 WO claimed
US-20120196024-A1 REMOVING COMPOUNDS FROM WINE CONSTELLATION WINES U.S., INC. (US) 2012-08-02 US claimed
US-5877389-A Process for the oxidative decomposition of organic compounds present in aqueous effluents ELF AQUITAINE (FR) 1999-03-02 US claimed
EP-0748296-B1 METHOD FOR OXIDATIVELY DECOMPOSING ORGANIC COMPOUNDS IN AQUEOUS EFFLUENTS ELF AQUITAINE (FR) 1997-08-27 EP claimed
US-4410738-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410737-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410739-A LEWIS ACID, NOBLE METAL CATALYST RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
JP-57075905-A None JP disclosed
EP-4610260-A1 ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Shanghai Shenshi Wise Technology Co., Ltd. (CN) 2025-09-03 EP disclosed
WO-2024088343-A1 ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海深势唯思科技有限责任公司 2024-05-02 WO disclosed
CN-117946111-A Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2024-04-30 CN disclosed
US-20180291129-A1 METHODS FOR PREPARATION OF MOLECULARLY IMPRINTED POLYMERS FOR WINE EXTRACTION THE TRUSTEES OF DARTMOUTH COLLEGE 2018-10-11 US disclosed
US-10000598-B2 Methods for preparation of molecularly imprinted polymers for wine extraction THE TRUSTEES OF DARTMOUTH COLLEGE (US) 2018-06-19 US disclosed
US-4540834-A HYDRODECHLORINATION OF POLYCHLOROPHENOL, HYDRIOTIC ACID RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-09-10 US disclosed
US-4410737-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed
US-4410738-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed
US-4410739-A LEWIS ACID, NOBLE METAL CATALYST RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed
US-4344848-A Procedure for purifying waste water in a floating layer reactor Enso- Gutzeit Osakeyhtio (FI) 1982-08-17 US disclosed
JP-S5775905-A S-SEC-BUTYL O-(4,5-DICHLORO-20METHOXYPHENYL) O-ETHYLPHOSPHOROTHIOLATE AND INSECTICIDE, ACARICIDE AND MENATOCIDE CONTAINING THE SAME KUMIAI CHEM IND CO LTD 1982-05-12 JP disclosed