Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.62 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 8/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398465 | 0.86 | PRSS1 (0.59) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8553223 | 0.85 | PRSS1 (0.63) | PRSS1PRSS2PRSS3LOXL2F10 | |
| Hydrochloric Acid SCHEMBL3295507 | 0.85 | PRSS1 (0.57) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8556051 | 0.82 | PRSS1 (0.59) | PRSS1PRSS2PRSS3LOXL2F10 | |
| Phenylmethanesulfonic Acid SCHEMBL7148383 | 0.82 | F2 (0.52) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL11547040 | 0.79 | F10 (0.61) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8075846 | 0.78 | CA2 (0.41) | PRSS1PRSS2PRSS3F2 | |
| Ammonia Solution, Strong SCHEMBL11392652 | 0.78 | F10 (0.59) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8559377 | 0.78 | LOXL2 (0.53) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358796 | 0.77 | PRSS1 (0.71) | PRSS1PRSS2PRSS3LOXL2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001087-A | INACTIVATION OF THROMBIN | THE UNITED STATES OF AMERICA (US) | 1977-01-04 | — | — | US | claimed |
| US-4150049-A | P-NITROPHENYL AMIDINOPHENYLMETHANESULFONATE, THROMBIN INACTIVATION | THE GOVERNMENT OF THE UNITED STATES (US) | 1979-04-17 | — | — | US | disclosed |
| US-4150049-A | P-NITROPHENYL AMIDINOPHENYLMETHANESULFONATE, THROMBIN INACTIVATION | THE GOVERNMENT OF THE UNITED STATES (US) | 1979-04-17 | — | — | US | disclosed |
| US-4001087-A | INACTIVATION OF THROMBIN | THE UNITED STATES OF AMERICA (US) | 1977-01-04 | — | — | US | disclosed |