Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553223 | 0.84 | PRSS1 (0.63) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8556017 | 0.83 | TSHR (0.58) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8170318 | 0.83 | TSHR (0.68) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL11548290 | 0.82 | PRSS1 (0.62) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8559377 | 0.80 | LOXL2 (0.53) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL11398465 | 0.80 | PRSS1 (0.59) | PRSS1PRSS2PRSS3LOXL2F10 | |
| Hydrochloric Acid SCHEMBL3295507 | 0.78 | PRSS1 (0.57) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8556179 | 0.76 | PRSS1 (0.52) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL16938221 | 0.76 | MMP2 (0.55) | TSHRHSD17B10IDO1 | |
| SCHEMBL13723492 | 0.76 | CCR2 (0.56) | TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |