Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531801 | 0.88 | ADORA3 (0.47) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL82055 | 0.88 | PPARG (0.53) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL8935937 | 0.88 | PPARG (0.53) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL2560059 | 0.87 | L3MBTL1 (0.50) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL16753083 | 0.87 | ADORA3 (0.46) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL3102154 | 0.87 | PPARA (0.64) | ADORA3PPARAPPARGMAPTMEN1 | |
| SCHEMBL4852302 | 0.87 | PPARA (0.49) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL11548490 | 0.86 | ADORA3 (0.61) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL2557598 | 0.84 | ADORA3 (0.44) | ADORA3PPARAPPARGELANEMAPT | |
| SCHEMBL10594998 | 0.83 | ADORA3 (0.43) | ADORA3PPARAPPARGELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | disclosed |