Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879122 | 0.92 | LMNA (0.56) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL11239642 | 0.92 | L3MBTL1 (0.56) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL11158149 | 0.92 | LMNA (0.56) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL10964710 | 0.92 | EPHX2 (0.62) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL11174260 | 0.89 | L3MBTL1 (0.53) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL5205374 | 0.89 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL9857703 | 0.89 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL18562096 | 0.89 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL9063261 | 0.89 | LMNA (0.63) | L3MBTL1LMNAKMT2AEPHX2TDP1 | |
| SCHEMBL403443 | 0.88 | IDH1 (0.55) | L3MBTL1LMNAKMT2AEPHX2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148915-A | ARTERIOSCLEROSIS AND HYPERLIPEMIA TREATMENT DIURETICS, ANTICHOLESTEROL AND ANTILIPEMIC | ALBERT ROLLAND, S.A. (FR) | 1979-04-10 | — | — | US | disclosed |