Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465519 | 0.99 | MAPT (0.42) | MAPTTHRBTP53GLACA12 | |
| SCHEMBL11503585 | 0.84 | CA12 (0.40) | MAPTTP53CA12CA2CA3 | |
| SCHEMBL11553588 | 0.80 | PTGS1 (0.56) | MAPTTP53GLACA12CA2 | |
| SCHEMBL11481868 | 0.79 | TP53 (0.42) | MAPTTP53JMJD6MAOBADORA3 | |
| SCHEMBL11548964 | 0.79 | MAOB (0.60) | MAPTTHRBTP53CA12CA2 | |
| SCHEMBL11018706 | 0.78 | GPR35 (0.58) | MAPTTP53GLAMAOBGPR35 | |
| SCHEMBL11152688 | 0.77 | GPR35 (0.46) | MAPTMAOBGPR35 | |
| SCHEMBL11548529 | 0.75 | TP53 (0.36) | MAPTTP53MAOBNPC1RAB9A | |
| SCHEMBL10688222 | 0.74 | MAOB (0.49) | MAPTTP53GLAMAOBNPC1 | |
| SCHEMBL11550765 | 0.73 | TP53 (0.37) | MAPTTP53MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | disclosed |